Equity Subscription and Issue of Warrants

Result of AGM

Holding(s) in Company

Total Voting Rights

Final results for the year ended 31 December 2021

Equity Subscription and Issue of Warrants

Equity Subscription and Issue of Warrants

Total Voting Rights

Holding(s) in Company

LIGHT system potential in delivering FLASH

Total Voting Rights

Video showcases progress on LIGHT system process

Operational update

Update re admission of Subscription Shares

Update re admission of Subscription Shares

Equity Subscription and Issue of Warrants

Total Voting Rights

£2m Subscription, Add'l Loan and Issue of Warrants

Advanced Oncotherapy (AVO) - LIGHT: regulatory update

Director/PDMR Notification

Director/PDMR Notification

Director/PDMR Notification

Operational update

Total Voting Rights

Exercise of Warrants and Issue of Equity

Total Voting Rights

Exercise of Warrants and Issue of Equity

Total Voting Rights

Technical update on delivery of first LIGHT system

Holding(s) in Company

Holding(s) in Company

Issue of warrants and equity and Loan Extension

Total Voting Rights

Advanced Oncotherapy (AVO): On the home straight

Holding(s) in Company

Exercise of Warrants and Issue of Equity

Holding(s) in Company

Presentation highlights LIGHT system superiority

Total Voting Rights

Interim Results

Exercise of Warrants and Issue of Equity

Update re admission of Subscription Shares

Update on admission of Subscription Shares

Exercise of Warrants and Issue of Equity

Advanced Oncotherapy (AVO) Funded to completion

Proposed subscription and issuance of shares

Result of AGM

Result of AGM

Holdings in company

Final Results for the year ended 31 December 2020

Saba Partners sign LOI for LIGHT system

Total Voting Rights

Exercise of Warrants and Issue of Equity

Exercise of Warrants and Issue of Equity

Total Voting Rights

Study shows the potential superiority of LIGHT

Exercise of Warrants and Issue of Equity

Total Voting Rights

Exercise of Warrants and Issue of Equity

Equity fundraise of c.5.9m

Exercise of Warrants and Issue of Equity

Technical update

Second Price Monitoring Extn

Price Monitoring Extension

Financing partnership agreement with DiaMedCare AG

Holding(s) in Company

Holding(s) in Company

Holding(s) in Company

Total Voting Rights

Equity fundraise of c.7.7m

Investor Day Update

Second Price Monitoring Extn

Price Monitoring Extension

Replacement: Grant of LTIP Options

Notice of Investor Day

Grant of LTIP Options

Interim Results

Directorate Appointment

Technical Development Update

Appointment of Joint Broker

Draw down from Nerano Pharma debt facility

Director/PDMR Shareholding

Result of AGM and Directorate Changes

Advanced Oncotherapy (AVO): End-goal fast approaching

Final Results for the year ended 31 December 2019

Strategic funding partnership and debt facility

Holding(s) in Company

Directorate Changes and Notice of Results

Holding(s) in Company

Total Voting Rights

Holding(s) in Company

Notice of GM and Posting of Circular

Further re Subscription and Issue of Equity

Proposed Subscription to raise c.£15 million

Q&A with Dr Martin Hall on Advanced Oncotherapy (AVO): Confidence in LIGHT gaining momentum

UHB and AVO to collaborate over LIGHT system

Advanced Oncotherapy (AVO): Confidence in LIGHT gaining momentum

Purchase of a LIGHT proton therapy system

Partnership with The London Clinic

Advanced Oncotherapy (AVO): Proving the accuracy and superiority of minibeams

Two-Year Collaborative Research Study

Holding(s) in Company

Total Voting Rights

Holding(s) in Company

Subscription to raise c.GBP 2.7 million

Advanced Oncotherapy (AVO): FLASH benefits from new US reimbursement

Total Voting Rights

Change of Broker

Total Voting Rights

Further re funding for first LIGHT system

Half-year Report

Exercise of Warrants and Issue of Equity

Total Voting Rights

Holding(s) in Company

Total Voting Rights and Directors' Shareholdings

Advanced Oncotherapy (AVO): Nearing the end-goal

Issue of equity and new debt facility

Price Monitoring Extension

Second Price Monitoring Extn

Result of AGM

AGM Statement & Technological update

Harley Street update

Final Results

Technological update

Total Voting Rights

Holding(s) in Company

Advanced Oncotherapy (AVO): Commercialising a breakthrough technology

Debt facility secured

Advanced Oncotherapy (AVO): Preparing for commercialisation

Senior Management Appointment

Price Monitoring Extension

Grant of options

Appointment of Nominated Adviser and Joint Broker

Schedule 2(g) Disclosure

Total Voting Rights and Significant Shareholdings

Schedule 2(g) Disclosure

Result of General Meeting

Advanced Oncotherapy (AVO): Important regulatory milestone: ISO approval

ISO 13485:2016 certification for medical devices

Launch of 2018 SAYE Scheme

Proposed Direct Subscription to raise £10.0m

Advanced Oncotherapy (AVO): Four components int...

Advanced Oncotherapy (AVO): Treatment planning ...

GPSL Research - Flash Note on AVO

Technological update

GPSL Research - Flash Note on AVO

Half-year Report

Technological update

Holding(s) in Company

Holding(s) in Company

Advanced Oncotherapy (AVO): Treatment planning ...

Completion of the £6.41m Placing

Advanced Oncotherapy (AVO): Treatment planning ...

Director Declaration

Exercise of Warrants and Issue of Shares

£6.41m Placing

Result of AGM

Second Price Monitoring Extn

Price Monitoring Extension

Second Price Monitoring Extn

Price Monitoring Extension

Second Price Monitoring Extn

Price Monitoring Extension

Directorate Changes

Final Results

Update on financing

Technological update

Director dealing

Result of Meeting

Completion of the Subscription Agreement

Holding(s) in Company

Hardman & Co Research: Confidence greatly boosted

Update on Distribution Agreement

Holding(s) in Company

GPSL Research on Advanced Oncotherapy Plc

UK assembly and testing site agreement

Update on Distribution Agreement Payment

Price Monitoring Extension